Publications

Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. mBio. 2017 Nov 28;8(6):e01872-17
Immunoinformatic Analysis of SARS-CoV-2 Nucleocapsid Protein and Identification of COVID-19 Vaccine Targets Oliveira SC, de Magalhães MTQ, Homan EJ. Front Immunol. 2020 Oct 28;11:587615. doi: 10.3389/fimmu.2020.587615
CD4+ T Cells in the Blood of MS Patients Respond to Predicted Epitopes From B cell Receptors Found in Spinal Fluid. Høglund RA, Bremel RD, Homan EJ, Torsetnes SB, Lossius A, Holmøy T. Front Immunol. 2020 Apr 9;11:598. doi: 10.3389/fimmu.2020.00598. eCollection 2020. PMID: 32328067
Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies. Xu-Monette ZY, Li J, Xia Y, Crossley B, Bremel RD, Miao Y, Xiao M, Snyder T, Manyam GC, Tan X, Zhang H, Visco C, Tzankov A, Dybkaer K, Bhagat G, Tam W, You H, Hsi ED, van Krieken JH, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Piris MA, Winter JN, Medeiros JT, Xu B, Li Y, Kirsch I, Young KH. J Immunother Cancer. 2019 Oct 22;7(1):272.
Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner. Høglund RA, Torsetnes SB, Lossius A, Bogen B, Homan EJ, Bremel R, Holmøy T. Int J Mol Sci. 2019 Sep 29;20(19). pii: E4843. doi: 10.3390/ijms20194843. PMID: 31569504
Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles. Whelan AO, Flick-Smith HC, Homan J, Shen ZT, Carpenter Z, Khoshkenar P, Abraham A, Walker NJ, Levitz SM, Ostroff GR, Oyston PCF.
Schistosoma mansoni SmKI-1 or Its C-Terminal Fragment Induces Partial Protection Against S. mansoni Infection in Mice. Morais SB, Figueiredo BC, Assis NRG, Homan J, Mambelli FS, Bicalho RM, Souza C, Martins VP, Pinheiro CS and Oliveira SC (2018). Front. Immunol. 9:1762. doi: 10.3389/fimmu.2018.01762
A Role for Epitope Networking in Immunomodulation by Helminths.. Homan EJ and Bremel RD (2018) Front. Immunol. 9:1763. doi: 10.3389/fimmu.2018.01763
Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. MBio. 2017 Nov 28;8(6). pii: e01872-17. doi: 10.1128/mBio.01872-17. PMID:29184017
In Silico Prediction Analysis of Idiotope -Driven T-B Cell Collaboration in Multiple Sclerosis. Høglund RA, Lossius A, Johansen JN, Homan J, Benth JŠ, Robins H, Bogen B, Bremel RD, Holmøy T. Front Immunol. 2017 Oct 2;8:1255. doi: 10.3389/fimmu.2017.01255. PMID:29038659
Extensive T-Cell Epitope Repertoire Sharing among Human Proteome, Gastrointestinal Microbiome, and Pathogenic Bacteria: Implications for the Definition of Self. Bremel RD, Homan EJ. Front Immunol. 2015 Oct 22;6:538. doi: 10.3389/fimmu.2015.00538. eCollection 2015. PMID: 26557118
Frequency Patterns of T-Cell Exposed Amino Acid Motifs in Immunoglobulin Heavy Chain Peptides Presented by MHCs. Bremel RD, Homan EJ. Front Immunol. 2014 Oct 28;5:541. doi: 10.3389/fimmu.2014.00541. eCollection 2014. Review. PMID: 25389426
Are cases of mumps in vaccinated patients attributable to mismatches in both vaccine T-cell and B-cell epitopes?: An immunoinformatic Homan EJ, Bremel RD. Hum Vaccin Immunother. 2014;10(2):290-300. doi: 10.4161/hv.27139. Epub 2013 Nov 25. PMID:24275080
Recognition of higher order patterns in proteins: immunologic kernels. Bremel RD, Homan EJ. PLoS One. 2013 Jul 29;8(7):e70115. doi: 10.1371/journal.pone.0070115. Print 2013. PMID: 23922927
Patterns of predicted T-cell epitopes associated with antigenic drift in influenza H3N2 hemagglutinin. Homan EJ, Bremel RD. PLoS One. 2011;6(10):e26711. doi: 10.1371/journal.pone.0026711. Epub 2011 Oct 24. PMID: 22039539
An integrated approach to epitope analysis II: A system for proteomic-scale prediction of immunological characteristics. Bremel RD, Homan EJ. Immunome Res. 2010 Nov 2;6:8. doi: 10.1186/1745-7580-6-8. PMID: 21044290
An integrated approach to epitope analysis I: Dimensional reduction, visualization and prediction of MHC binding using amino acid principal components and regression approaches. Bremel RD, Homan EJ. Immunome Res. 2010 Nov 2;6:7. doi: 10.1186/1745-7580-6-7. PMID: 21044289